Sirtuin – Wikipedie
Sirtuiny (SIR či Sir2 proteiny) představují skupinu enzymů (ze skupiny NAD+-závislých deacetyláz), které odstraňují acetylové a další kyselinové zbytky z modifikované aminokyseliny lysin, a tím regulují široké spektrum buněčných pochodů…
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About Us – National Saddlery Company
In the early 1900's, the Denu family (father and sons) were highly regarded as master saddle and leather craftsmen. The Leather Workers’ Journal, Volume 15-16, September 1912, reported that "Brothers Orvis and Earl Denu retired from the…
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Multivalent interactions drive nucleosome binding and efficient…
The protein deacetylase SIRT6 maintains cellular homeostasis through multiple pathways that include the deacetylation of histone H3 and repression of transcription. Prior work suggests that SIRT6 is associated with chromatin and can…
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Structure and Biochemical Functions of SIRT6 - PMC
SIRT6 is a member of the evolutionarily conserved sirtuin family of NAD+-dependent protein deacetylases and functions in genomic stability and transcriptional control of glucose metabolism.
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Eileen Galindo: Nejlepší filmy a seriály | Kinobox.cz
Eileen Galindo - filmy a seriály
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Non-canonical Mtorc2 signaling regulates brown adipocyte lipid…
Mtorc2 controls glucose and lipid metabolism, but the mechanisms have been unclear. Here, we show that conditionally deleting the essential Mtorc2 subunit Rictor in murine brown adipocytes inhibits de novo lipid synthesis, promotes lipid…
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Autoacetylation of the Histone Acetyltransferase Rtt109 - PMC
Rtt109 is a yeast histone acetyltransferase (HAT) that associates with histone chaperones Asf1 and Vps75 to acetylate H3K56, H3K9, and H3K27 and is important in DNA replication and maintaining genomic integrity.
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SIRT6 suppresses pancreatic cancer through control of Lin28b…
Chromatin remodeling proteins are frequently dysregulated in human cancer, yet little is known about how they control tumorigenesis. Here, we uncover an epigenetic program mediated by the NAD+-dependent histone deacetylase Sirtuin 6 (SIRT6…
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Walkden - Wikipedia
Walkden is a town [2 ] in the City of Salford in Greater Manchester, England, [3 ] six miles (ten kilometres) northwest of central Salford, and seven miles (eleven kilometres) of Manchester.
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Nathan Shock Centers | Home
American Federation for Aging Research (AFAR) will lead NSC3 collaboration and training activities with $5.7 million NIH award.
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