Josko Osredkar, Senior Concuillor | Cited by 4,251 | of Ljubljana University Medical Centre, Ljubljana (UMC) | Read 232 publications | Contact Josko Osredkar
I am Professor of Paediatrics at Karolinska Institutet since 2011.I am a paediatric oncologist with a special interest in brain tumours. Between 2016 and 2024 I was Vice Head of the Department of Women's and Children's Health.
I focussed my research efforts on two major topics: nutrigenomic and signaling events taking place under L-carnitine deficiency and subsequent supplementation and generation of superactive human thymidine kinase 1 (TK1) mutants and their…
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Mendelian randomization offers novel insights into the genetic factors that influence the aging process through early-life reproductive events, providing robust evidence for the antagonistic pleiotropy theory in humans.
However, no standard method for the extraction or for the assay has been developed and TK determination in extracts from cells and tissues have not been validated in relation to any specific clinical question, see however Arnér et al. [111…