Díky podpoře Alderana Cyby, vévody z Massy, a později jeho vdovy, Ricciardie Gonzagy, začal v roce 1746 studovat pod vedením Francesca Durante na Conservatorio di Santa Maria di Loreto v Neapoli, kterou dokončil v roce 1750 a dál na škole…
Guglielmi was born into the Guglielmi family of musicians in Massa. [1 ] His father, Jacopo Guglielmi, was a composer and conductor of the orchestra in the court of the Duke of Massa.
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Guglielmi composed 33 opere serie. However, he was better known for the style of his less formal works, writing 25 opere buffe (designated as commedia per musica), 25 drammi giocosi, six intermezzi, five farse or farsette, and one serenata.
I Guglielmi, Massa, 1978; · J. L. Jackman, Pietro Alessandro Guglielmi, in The New Grove Dictionary of music and musicians, vol. VII, Londra, 1980, pp. 793-798; · G. Magri, Pietro Alessandro Guglielmi, Massa, 1984; · R.