Suppression of inflammation by a synthetic histone mimic - PMC
Interaction of pathogens with cells of the immune system results in activation of inflammatory gene expression. This response, while vital for immune defence, is frequently deleterious to the host due to the exaggerated production of…
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Susumu Hirose | Professor Emeritus | Ph.D. | National Institute…
I am studying epigenetics and chromatin focusing on supercoiling factor (SCF), MBF1 and FACT.
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Ektopická exprese antigenů v thymu – Wikipedie
Ektopická exprese antigenů v thymu (z angl. ectopic expression, v novější literatuře pak promiscuous gene expression) je procesem, během kterého dochází ke generování tisíců tkáňově specifických antigenů (TSA), které jsou v těle produkovány…
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In Vitro Transcription Research Papers - Academia.edu
View In Vitro Transcription Research Papers on Academia.edu for free.
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Non-coding RNAs as regulators of embryogenesis - PMC
Non-coding RNAs (ncRNAs) are emerging as key regulators of embryogenesis. They control embryonic gene expression by several means, ranging from microRNA-induced degradation of mRNAs to long ncRNA-mediated modification of chromatin.
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Minireview: Latest Perspectives on Antiinflammatory Actions of…
Taking into consideration that glucocorticoid (GC) hormones have been used clinically for over half a century and that more than 20 yr have passed since the cloning of the GC receptor (GR), it is hard to imagine that novel aspects in the…
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NF-kB directs dynamic super enhancer formation in inflammation…
Proinflammatory stimuli elicit rapid transcriptional responses via transduced signals to master regulatory transcription factors. To explore the role of chromatin-dependent signal transduction in the atherogenic inflammatory response, we…
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SOCS3 Inhibits Antiviral IFN-β Signaling to Enhance HIV-1…
HIV-1 replication within macrophages of the CNS often results in cognitive and motor impairment, which is known as HIV-associated dementia (HAD) in its most severe form. IFN-β suppresses viral replication within these cells during early CNS…
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Ignacia Echeverria, PhD - Homepage
I obtained a Ph.D. in Molecular Biophysics at Johns Hopkins University and a bachelors degree in Physics at Pontificia Universidad Católica de Chile.
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