Among Snare proteins mediating synaptic vesicle fusion, syntaxin-1 uniquely includes an N-terminal peptide (‘N-peptide’) that binds to Munc18-1, and a large, conserved Habc-domain that also binds to Munc18-1.
Recent randomized controlled trials have demonstrated the effectiveness of the collaborative dementia care model targeting both patients suffering from dementia and their informal caregivers.
Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during mitosis.
The area has seen many periods of revival and decline in the past 200 years since its opening. [1 ] The area is currently under redevelopment as part of the Perkins, Somerset Oldtown (PSO) Transformation Plan.