Accumulation of protein aggregates is the leading cause of cellular dysfunction in neurodegenerative disorders. Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease, Prion disease and motor disorders such as amyotrophic…
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin.
RNA-binding proteins (RBPs) are crucial in disease as they regulate the biological functions of RNA. However, their role in coronary artery disease (CAD) pro...
Dong Li, PhD, is a research scientist with the Jill and Mark Fishman Center for Lymphatic Disorders and the Division of Human Genetics at Children's Hospital of Philadelphia. Dr. Li’s current research focuses on novel human disease gene…