The primary data for this and other partial lists is based on JPL's "Small-Body Orbital Elements" [1 ] and data available from the Minor Planet Center. [2 ] [3 ] Critical list information is also provided by the MPC, [2 ] [3 ] unless…
Content experts: Whit Athey, Katherine Hope Borges, Rebekah Canada, Phil Goff, Gareth Henson, Charles Moore, Ana Oquendo Pabon, David F. Reynolds, Bonnie Schrack, Ann Turner, Victor Villarreal, Vincent Vizachero, David Wilson.
Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and dietary consumption of these structurally diverse compounds is associated with multiple health benefits including increased lifespan, decreased…
In this review, we will discuss small molecules that recent evidence suggests may be capable of improving health and extending lifespan in mammals, focusing particularly on resveratrol, rapamycin, and metformin.
Resveratrol was first isolated in 1939 by Takaoka from Veratrum grandiflorum O. Loes. Following this discovery, sporadic descriptive reports appeared in the literature. However, spurred by our seminal paper published nearly 60 years later…
Noble gases (Ngs) are the least reactive elements in the periodic table towards chemical bond formation when compared with other elements because of their completely filled valence electronic configuration.
Resveratrol induces mitochondrial biogenesis and protects against metabolic decline but whether SIRT1 mediates these benefits is the subject of debate. To circumvent the developmental defects of germ-line SIRT1 knockouts, we have developed…
Hoover PJ, Raparia C, Lieb DJ, Tzur Y, Kang J, Arazi A, Leavitt R, Mishra R, Shah SI, Simmons D, Li S, Peters M, Eisenhaure T, Few-Cooper TJ, Gurajala SS, Sonny A, Hodgin JB, Berthier CC, Guthridge JM, Fava A, Clancy RM, Putterman C…